Go to Start > Administrative Tools > Internet Information Services (IIS) Manager.
Click on the +
symbol next to the computer name (the U number) to expand the menu.
IIS Manager overview
Create a new web site by right-clicking on Site
then Add Web Site...
For the Site name
and Host name
fill in domain.com where domain.com is your domain name.
Add Web Site window
For the Physical path: next to the ... of the text box, click on either Data (D:) or another drive letter other then System (C:). The C: drive is for system data and not very large.
Click on Make New Folder
and type in the new folder name. You can do this again to create a subfolder by clicking on the folder you just created and clicking on Make New Folder
a second time.
Click on OK
Browse For Folder
Now you can upload the files using either remote desktop or setup the server as an ftp server. If you are only uploading files for the website, use remote desktop. If the person uploading the files has poor Internet connection or you do not want to give remote desktop access, then setup ftp.